Dr. Saami Khalifian
Dr. Saami Khalifian
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Beyond Botox: Cutting-Edge Ways to Naturally Boost Your Collagen

Discover cutting-edge ways to naturally boost collagen and rejuvenate your skin—no Botox required. Learn how biostimulators like Sculptra® and Radiesse®, advanced treatments like Tixel® and PRP, and emerging options like Exosomes and Renuva® work to enhance your skin’s elasticity, volume, and radiance. Explore how a personalized, multimodal approach at SOM Aesthetics can help you achieve long-lasting, natural-looking results.

4
 min read
Patient after receiving cosmetic treatments in San Diego

At SOM Aesthetics, we believe great skin doesn’t begin and end with Botox®. While neuromodulators like Botox and Dysport® have their place, the future of skin rejuvenation lies in supporting your body’s natural regenerative abilities—especially its ability to produce collagen.

Collagen is the structural foundation of youthful skin. It gives your face volume, elasticity, and strength. As we age, our collagen production slows down, leading to fine lines, wrinkles, and sagging. But thanks to major advances in regenerative aesthetics, you can now stimulate collagen naturally for long-lasting, progressive results that look and feel like you.

Harnessing Biostimulation: Sculptra & Radiesse

Unlike traditional fillers, Sculptra® and Radiesse® work by encouraging your body to make its own collagen over time.

Sculptra uses poly-L-lactic acid (PLLA) to stimulate deep collagen production. Rather than filling lines immediately, it rebuilds volume gradually, leading to a natural, lifted look that evolves over months. It’s ideal for hollow cheeks, temples, jawline contouring, and skin that’s starting to lose elasticity.

Radiesse is made of calcium hydroxylapatite microspheres and works both immediately and over time. When diluted for skin tightening, it enhances elasticity and skin texture in often-overlooked areas like the neck, décolletage, and hands.

Next-Level Technology: Tixel & PRP

Tixel® is a non-laser, non-invasive skin resurfacing treatment that uses thermo-mechanical energy to open microchannels in the skin—boosting collagen production and increasing absorption of serums. It’s safe for all skin types, with minimal downtime and glowing, smooth results.

PRP (Platelet-Rich Plasma) taps into your body’s own healing mechanisms. We draw your blood, isolate the platelets, and reintroduce them to targeted areas to accelerate tissue regeneration and collagen production. When paired with microneedling or Tixel, PRP supercharges your skin’s recovery and enhances results.

Emerging Powerhouses: Exosomes & Renuva

Exosomes are one of the most promising developments in regenerative aesthetics. These cell-derived messengers are packed with growth factors and healing signals. When applied after treatments like Tixel or microneedling, they amplify skin renewal and collagen synthesis, improving results while reducing downtime.

Renuva® is another innovation—an injectable matrix made from donated fat tissue that stimulates your body to produce its own fat and collagen. It’s perfect for correcting small volume losses or refining previous filler results, and the effects are long-lasting and completely natural.

A Personalized Approach to Collagen Health

At SOM Aesthetics, we don’t just offer treatments—we create comprehensive, custom treatment plans rooted in science and empathy. Every consultation begins with a 45-minute session that includes VISIA skin analysis to uncover underlying concerns. From there, Dr. Saami Khalifian or our expert nurse injector, Selena Lam, will design a multimodal plan based on your anatomy, goals, and how you want to feel when you look in the mirror.

Often, our most effective collagen-boosting results come from combining treatments. For example, pairing Sculptra with Tixel and Exosomes can deliver deep volume restoration, surface refinement, and accelerated healing in a way that a single treatment simply can’t.

When to Start? Now.

Collagen production starts to decline in your late 20s—but it’s never too late (or too early) to begin regenerative treatments. Whether you’re looking to maintain youthful skin, address early signs of aging, or enhance results from past treatments, boosting your own collagen is the most natural and sustainable way to rejuvenate.

Experience the SOM Method

Dr. Saami's vision for aesthetic medicine is rooted in precision, artistry, and care. As the Executive Medical Director of Allergan Medical Institute—the company behind renowned products like Botox and Juvederm—his influence extends globally through developing injection protocols and training medical providers worldwide. A double board-certified dermatologist trained at Harvard and Johns Hopkins, Dr. Saami combines his exceptional credentials with a truly innovative and personalized approach to aesthetic treatments.

For personalized recommendations, schedule a consultation at SOM Aesthetics to take your first steps toward going beyond Botox.

To learn more about rise of natural collagen boosting treatments, check out this study from the National Institute of Health